<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="allergy-and-immunology" lang="en"> <front> <journal-meta> <journal-id journal-id-type="publisher">JOHS</journal-id> <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id> <journal-title-group> <journal-title>Journal of HealthCare Sciences</journal-title> <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title> </journal-title-group> <issn pub-type="ppub">2231-2196</issn> <issn pub-type="opub">0975-5241</issn> <publisher> <publisher-name>Radiance Research Academy</publisher-name> </publisher> </journal-meta> <article-meta> <article-id pub-id-type="publisher-id">359</article-id> <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2024.41238</article-id> <article-id pub-id-type="doi-url"/> <article-categories> <subj-group subj-group-type="heading"> <subject>Allergy and Immunology</subject> </subj-group> </article-categories> <title-group> <article-title>Ethics of Organ Donation and Transplant Allocation Policies </article-title> </title-group> <contrib-group> <contrib contrib-type="author"> <name> <surname>Alnaim</surname> <given-names>Malak Meshary</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alqahtani</surname> <given-names>Manar Ali</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alsultan</surname> <given-names>Nada Fahad</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alruwaithi</surname> <given-names>Ziad Abdulmoti</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alhazmi</surname> <given-names>Hatim Khalid</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alalwani</surname> <given-names>Mohammed Anwar</given-names> </name> </contrib> </contrib-group> <pub-date pub-type="ppub"> <day>30</day> <month>12</month> <year>2024</year> </pub-date> <volume>4</volume> <issue>12</issue> <fpage>938</fpage> <lpage>944</lpage> <permissions> <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement> <copyright-year>2009</copyright-year> <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"> <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p> </license> </permissions> <abstract> <p>Organ donation and transplantation have transformed modern medicine by offering life-saving solutions for patients with end-stage organ failure. Despite these advances, a significant gap persists between organ demand and availability, raising complex ethical challenges. Central to these challenges are principles of autonomy, altruism, and informed consent, which guide the decision-making process in organ donation. While presumed consent policies aim to address shortages, they have sparked debates regarding respect for individual autonomy and cultural differences. Similarly, incentivized donation programs, although promising, pose ethical dilemmas around coercion and exploitation. In transplant allocation, the balance between equity and utility remains contentious. Allocation systems strive to provide fair access while maximizing the overall benefit by prioritizing patients likely to achieve favorable outcomes. However, socioeconomic and geographic disparities often result in inequitable access to transplantation, disproportionately affecting vulnerable populations. Broader sharing policies and tailored scoring systems have been introduced to mitigate these disparities, but challenges in their implementation persist. Cultural and socioeconomic factors further influence ethical decision-making, impacting public perceptions of organ donation and the ability to provide informed consent. Cultural beliefs, language barriers, and socioeconomic inequities hinder donation rates and exacerbate disparities in access to transplantation. Educational campaigns and policy reforms that address these barriers are crucial for fostering trust and promoting equitable practices. Advancements in medical science, such as xenotransplantation and bioprinting, offer potential solutions to alleviate organ shortages but introduce additional ethical challenges. These include concerns related to safety, equitable access, and the risk of exacerbating existing disparities. A holistic approach to organ donation and allocation should incorporate ethical principles, acknowledge cultural differences, and address systemic inequalities. Such efforts are essential to ensuring that organ transplantation evolves in a manner that is both fair and sustainable. </p> </abstract> <kwd-group> <kwd>organ donation</kwd> <kwd> transplant allocation</kwd> <kwd> ethics</kwd> <kwd> equity</kwd> <kwd> informed consent</kwd> </kwd-group> </article-meta> </front> </article>