<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="emergency-medicine-and-critical-care" lang="en">
<front>
<journal-meta>
<journal-id journal-id-type="publisher">JOHS</journal-id>
<journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id>
<journal-title-group>
<journal-title>Journal of HealthCare Sciences</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">2231-2196</issn>
<issn pub-type="opub">0975-5241</issn>
<publisher>
<publisher-name>Radiance Research Academy</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">397</article-id>
<article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2025.50403</article-id>
<article-id pub-id-type="doi-url"/>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Emergency Medicine and Critical Care</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>The Effect of Endotracheal Intubation on Mortality of COVID-19 Infected Patients
</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Jamjoom</surname>
<given-names>Maan</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Altirkistani</surname>
<given-names>Bsaim Abdulsalam</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Allhybi</surname>
<given-names>Abdulaziz Khalid</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Morya</surname>
<given-names>Roaa Emad</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Babour</surname>
<given-names>Razan Rafat</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Alenezi</surname>
<given-names>Fares Abdullah</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mohtasib</surname>
<given-names>Malek Yahya</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>BinShihon</surname>
<given-names>Malak Ahmed</given-names>
</name>
</contrib>
</contrib-group>
<pub-date pub-type="ppub">
<day>30</day>
<month>04</month>
<year>2025</year>
</pub-date>
<volume>5</volume>
<issue>4</issue>
<fpage>144</fpage>
<lpage>150</lpage>
<permissions>
<copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement>
<copyright-year>2009</copyright-year>
<license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p>
</license>
</permissions>
<abstract>
<p>Background: Coronavirus disease 2019 (COVID-19) causes respiratory complications, which may lead to as severe hypoxemia and acute respiratory distress syndrome. Increased in mortality in COVID-19 patients who were older than 65, patients with comorbidities, and patients who developed acute respiratory distress syndrome (ARDS) predisposed to the need for invasive procedures such as intubation as part of the bundle of management. Therefore, this study aimed to address the impact and mortality of endotracheal intubation on COVID-19 patients.
Methods: This single-center retrospective cohort study included all COVID-19 intubated patients from early 2020 to January 2023. The targeted data was retrieved from the electronic medical records and then analyzed using JMP Statistical Software. Categorical variables were presented as frequency (%), while mean and standard deviation were used for continuous variables. A logistic regression was utilized to predict the mortality of these patients.
Results: A total of 2867 patients had COVID-19, out of which 47 were intubated and included in this study. Males constituted more than half of the included patients; 30 (63.83%). The majority of patients, 28 (59.57%), had opacifications on chest x-ray. Most patients, 30 (63.83%), were hospitalized for less than or equal to 30 days. There were 29 (61.70%) patients deceased during their presentation, out of which 18 (62.07%) were males. Logistic regression showed that longer hospital stays, hypotension, and hypoxemia after intubation were associated with higher odds of mortality, but none reached statistical significance.
Conclusion: This study provides valuable insights into the clinical characteristics and mortality of intubated COVID-19 patients. The high mortalities among intubated COVID-19 patients were reported and in parallel to previous studies. Therefore, it is recommended that further studies with larger sample sizes and multi-centers studies be conducted to accurately identify the burden and mortality of intubation on COVID-19 patients.
</p>
</abstract>
<kwd-group>
<kwd>Mortality</kwd>
<kwd> COVID-19</kwd>
<kwd> Intubation</kwd>
<kwd> Mortality</kwd>
<kwd> Emergency</kwd>
</kwd-group>
</article-meta>
</front>
</article>