<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="anaesthesia" lang="en"> <front> <journal-meta> <journal-id journal-id-type="publisher">JOHS</journal-id> <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id> <journal-title-group> <journal-title>Journal of HealthCare Sciences</journal-title> <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title> </journal-title-group> <issn pub-type="ppub">2231-2196</issn> <issn pub-type="opub">0975-5241</issn> <publisher> <publisher-name>Radiance Research Academy</publisher-name> </publisher> </journal-meta> <article-meta> <article-id pub-id-type="publisher-id">433</article-id> <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2025.50901</article-id> <article-id pub-id-type="doi-url"/> <article-categories> <subj-group subj-group-type="heading"> <subject>Anaesthesia</subject> </subj-group> </article-categories> <title-group> <article-title>Safety and Efficacy of Regional Blocks in Pediatric Day Surgery Procedures </article-title> </title-group> <contrib-group> <contrib contrib-type="author"> <name> <surname>Alrumaihi</surname> <given-names>Talal Sulaiman</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Ghunaim</surname> <given-names>Abdullah Ahmed</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Amoudi</surname> <given-names>Jameel Hosni</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alqabli</surname> <given-names>Mohammed Sameer</given-names> </name> </contrib> </contrib-group> <pub-date pub-type="ppub"> <day>17</day> <month>09</month> <year>2025</year> </pub-date> <volume>5</volume> <issue>9</issue> <fpage>468</fpage> <lpage>475</lpage> <permissions> <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement> <copyright-year>2009</copyright-year> <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"> <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p> </license> </permissions> <abstract> <p>Pediatric day surgery is increasingly recognized worldwide, attributed to its lower costs, reduced disturbance, and abbreviated hospital stays. Addressing surgical pain is crucial in encouraging immediate recovery, achieving discharge criteria, and ensuring parental satisfaction. Perioperative analgesia in pediatrics is based on the use of regional anesthesia to target pain and reduce the dose of opioids that are used systemically as well as the side effects of those opioids. This narrative review summarizes the recent regional block safety and efficacy evidence for pediatric day surgery. Caudal, peripheral nerve, and fascial plane blocks are prioritized. Recently, conducted research has demonstrated that regional anesthesia is more effective than systemic anesthesia in managing pain. Regional anesthesia effectively manages pain, reduces reliance on opioid pain medications, and offers a longer duration of pain relief. The reduction of nausea, vomiting, sedation, and other opioid-related side effects is an advantage of regional anesthesia that speeds up the milestones associated with discharge. Regional blocks for children are safe and effective in reducing the risk of complications when performed by clinicians who have received professional training, especially with ultrasound assistance, which improves anatomical visualization. In pediatric day surgical procedures, regional anesthetic improves patient comfort, recovery quality, and parental satisfaction in outpatient care. Selection of the right block depends on surgical site, patient age, and expertise. To maintain high standards of care, institutions must support training, pediatric-specific equipment, and safety protocols. This review aims to provide an updated synthesis of regional block safety and efficacy in pediatric day surgery to enable anesthesiologists to make evidence-based decisions. Future research should include pediatric-specific trials of emerging fascial plane blocks, long-acting local anesthetics, and regional anesthesia in enhanced recovery after surgery (ERAS) pathways. These advances may improve outcomes, reduce opioid exposure, and expand regional techniques in pediatric ambulatory anesthesia. </p> </abstract> <kwd-group> <kwd>safety</kwd> <kwd> efficacy</kwd> <kwd> regional blocks</kwd> <kwd> pediatric</kwd> <kwd> children</kwd> <kwd> day surgery</kwd> <kwd> procedures</kwd> </kwd-group> </article-meta> </front> </article>