<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="cardiology" lang="en"> <front> <journal-meta> <journal-id journal-id-type="publisher">JOHS</journal-id> <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id> <journal-title-group> <journal-title>Journal of HealthCare Sciences</journal-title> <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title> </journal-title-group> <issn pub-type="ppub">2231-2196</issn> <issn pub-type="opub">0975-5241</issn> <publisher> <publisher-name>Radiance Research Academy</publisher-name> </publisher> </journal-meta> <article-meta> <article-id pub-id-type="publisher-id">435</article-id> <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2025.50903</article-id> <article-id pub-id-type="doi-url"/> <article-categories> <subj-group subj-group-type="heading"> <subject>Cardiology</subject> </subj-group> </article-categories> <title-group> <article-title>A Case Report of Acute Myocardial Infarction in a Patient with History of Herpes Zoster Infection </article-title> </title-group> <contrib-group> <contrib contrib-type="author"> <name> <surname>Alshehri</surname> <given-names>Mohammed A.</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alshehri</surname> <given-names>Abdullah M.</given-names> </name> </contrib> </contrib-group> <pub-date pub-type="ppub"> <day>21</day> <month>09</month> <year>2025</year> </pub-date> <volume>5</volume> <issue>9</issue> <fpage>483</fpage> <lpage>487</lpage> <permissions> <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement> <copyright-year>2009</copyright-year> <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"> <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p> </license> </permissions> <abstract> <p>Background: Patients with history of herpes zoster (HZ) infection were found to have an increased long-term risk of major cardiovascular events. The association between myocardial infarction (MI) and HZ infection is an area of rising research interest. While HZ infection primarily has both dermatological and neurological manifestations, studies have increasingly shown that it may also be linked to increased cardiovascular risk, particularly acute MI and stroke. Case presentation: Here we report a case of acute MI in a 68-year-old male patient who has a history of HZ infection and received the booster dose of HZ vaccine (Shingrix) 24 hours prior to his presentation with acute MI. Moreover, this case report of acute myocardial injury secondary to acute None-ST segment elevation MI following Shingrix vaccine in a patient with history of HZ infection helps in establishing the relationship between HZ infection and its cardiovascular effects. Conclusion: To conclude, health care providers should be aware of the increased risk of cardiovascular events in patients with history of HZ infection and the rare side effect of vaccines to properly evaluate patient who presented with suspicious symptoms following vaccine administration. </p> </abstract> <kwd-group> <kwd>Herpes zoster</kwd> <kwd> Herpes zoster vaccination</kwd> <kwd> Myocardial infarction</kwd> <kwd> Acute coronary syndrome</kwd> </kwd-group> </article-meta> </front> </article>